Stanford's Team for the International Genetically Engineered Machines competition
iGEM is a global synthetic biology competition where the world’s top student-led synthetic biology teams work to design, build, and test novel biological innovations. Projects culminate in the Fall at the iGEM Jamboree, where teams fly into Boston for a weekend of presenting, networking, competition, and fun.
We are in the midst of recruiting a team that will work this spring and full-time this summer to ideate, troubleshoot, and execute a project with the utmost standard of excellence in order to bring Stanford to the forefront of the iGEM 2020 competition.
iGEM stands for the International Genetically Engineered Machines competition, an international competition where teams create, test, and present their
own bioscience research projects involving genetic devices. The Stanford team is composed of 7-12 undergraduate students, who work on developing a project
through a needs finding process and presenting at the annual Giant Jamboree, located in Boston. Click here to learn more .
2019 Project Abstract:
The current paradigm of part creation, characterization, and documentation is extremely rate-limiting for scientific discovery.
The 2019 Stanford iGEM team envisioned an alternative model for facile part creation where final genetic device performance necessarily
conforms to initial design specifications. To make this future a reality, we focused on developing self-selecting systems (SSS):
directed evolution platforms that selectively amplify the genotypes corresponding to desirable phenotypes. Specifically, we
developed Directed Chassis-agnostic Evolution, or DiCE, a novel, easy-to-implement selection-based directed evolution
platform built off Qbeta replicase, an RNA-based RNA polymerase, capable of evolving proteins in vivo and in vitro. Furthermore, we generated standard
selection schema compatible with PREDCEL (Heidelberg 2017) to expand the range of synthetic biological parts that can be created by any SSS.
Taken together, our work on SSS presents a foundational advance towards a future where part creation is easier, faster, and more accessible.
Learn more .
The iGEM 2020 Application is live! Click this link
to access the application! All relevant application information and requirements are listed on the Google Form itself.
The 2019 Team was composed of 6 full time undergraduates, a volunteer member, 3 high school student interns, and
received the help of many sponsors, graduate student mentors, as well as PIs. Learn more about our team
Interested in Mentoring?
Our team depends on the generous support of a team of graduate student (and beyond!) mentors. Mentorship can range from being a Stanford iGEM Consultant (a handful of guiding conversations over the summer offering your expertise), to a Stanford iGEM Mentor (more regular support helping to oversee project trajectory and/or giving wetlab advice).
Interested in helping guide our team? Please contact this email: email@example.com to get in touch
Check out our mentors from last year here.
Want to Support Us?
Want to support us? Get in contact with us at firstname.lastname@example.org and help our team succeed in the 2020 season!